How does casein affect autism
Similarly, Arnold, Hyman, Mooney, and Kirby found that children on GFCF diets have significantly poorer protein nutrition than children on unrestricted diets, potentially placing developing brains at risk for protein malnutrition. In a comprehensive review of research regarding feeding problems and nutrient status of children with ASD, Sharp and colleagues found children with ASD are significantly more likely to experience feeding problems as compared to their peers.
Additionally, a nutrient analysis indicated a significantly lower intake of calcium and protein for children with ASD in general. Thus, a child with ASD may already be at risk for detrimental health side effects associated with a diet low in calcium, vitamin D, and protein Sharp et al. A child with ASD who also consumes a GFCF diet may essentially double his or her risk for detrimental health side-effects associated with a diet low in essential nutrients.
If one felt compelled to investigate these diets further, future research may focus on: a using a larger sample size for group studies, b conducting studies utilizing within-subjects designs to control for individual differences often seen across individuals with ASD, c conducting longer baseline and test periods to ensure the diet is in place long enough to capture any results, and d continuing to utilize direct behavior measurements and double-blind tests Elder, Additionally, future research may consider whether positive outcomes associated with GFCF diets are due to the absence of gluten and casein or simply due to a more nutritious diet that may be associated with a diet free of gluten and casein.
Because children with ASD are likely to consume a limited diet that includes a preference for snack foods , a GFCF diet may simply result in the consumption of a more nutritiously balanced diet because it likely eliminates foods low in fiber or high in fat and increases the consumption of fruits and vegetables.
Additionally, it may eliminate excessive intake of dairy products which can lead to constipation. It is possible that positive behavior change may be observed simply because the individual is consuming a healthier diet and thus, feels better physically e. If any child is allergic to gluten or casein, then the GFCF diet should be considered.
However, without a clear medical necessity, until further research suggests a strong causal relationship between the GFCF diet and specific and measurable positive changes in socially important targets of individuals with autism, it should not be used to treat this disorder Mulloy et al.
The biological findings surrounding the opioid-excess theory are limited and mixed. The behavioral changes resulting from the use of a GFCF diet with children with autism are limited and mixed. The financial cost and associated health risks further suggest avoiding a GFCF diet as a treatment for autism.
Diet changes should always be decided upon and closely monitored by a physician. Next, a second study was initiated, funded by the Spanish Association of Child and Adolescent Psychiatry AEPNyA , in which 37 children and adolescents diagnosed with autism-spectrum disorders participated. This sample followed the same procedure, except for a longer duration one special diet for six months, then the other special diet, again for six months.
Variables relating to the efficacy, risk, and safety of following these diets were studied. In addition to eliminating gluten and casein for a sufficient period of time at least six months , future studies should include placebo and double-blind elements, as well as other biological markers to better define the subjects who may benefit from these diets.
But the researchers caution that larger studies are needed to determine whether there are small subgroups of children who would benefit. The diet is popular among families who have children with autism. Some propose that gluten a protein found in wheat and some other grains and casein a protein found in dairy products can worsen autism symptoms by causing inflammation in the gut that spreads to the brain.
The study findings appear online in the Journal of Autism and Developmental Disorders. They call for larger studies enrolling more children to see if there is a small subset of children whose autism symptoms are helped by the diet.
As of , scientific research has not been conclusive on the benefits versus the detriments of the GFCF diet or whether people with autism are truly more sensitive to gluten. As long as you ensure that your child eats a balanced diet otherwise, you can try eliminating gluten, casein, or both. Be aware that foods in these two groups are typical sources of important proteins for development and growth, so you should find a way to replace them with other proteins.
There could be several reasons for this, including positive behavioral changes from the parents, behavioral interventions associated with adjusting meals for children, or actual gastrointestinal improvements. To narrow down the cause, parents could gradually reintroduce gluten or casein and see if negative effects occur. How Does Gluten Impact Autism?
A study published in analyzed blood samples from 37 children with autism, 27 of their unaffected siblings, and 76 healthy children in the control group.
The study examined the samples for antibodies that indicated celiac disease, an autoimmune condition that leads to inflammation in the gut. Researchers found higher rates of celiac antibodies in the children with autism, suggesting that at least a gluten sensitivity similar to celiac was causing some gastrointestinal distress.
They stated that follow-up studies were needed. A meta-survey published later in examined several Swedish databases for diagnoses of celiac disease among people who had been diagnosed with autism. They gathered information on , people and found that people with celiac were no more likely to also have autism than the general population. About 44 out of , people were diagnosed with autism before being diagnosed with celiac disease.
About 48 people in , were diagnosed with autism but not celiac disease. The study did show, unusually, that people with autism were more likely to have a positive blood test for celiac antibodies.
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